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Myelodysplastic syndrome literature review

Metrics details. Schistocytosis, which is often observed in thrombotic thrombocytopenic purpura TTP patients, is a rare complication in myelodysplastic syndrome MDS patients. We report on a year-old man with progressive anemia and thrombocytopenia. Schistocytes were observed in his peripheral blood; consciousness disturbance, renal insufficiency, and fever were subsequently observed, fulfilling the classic pentad of TTP. He also showed massive hematuria, headache, chest pain, and abdominal pain, and brain magnetic resonance imaging scan demonstrated small infarctions. Cefmetazole was not effective, and there was no focus of infection.
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Familial myelodysplastic syndromes: a review of the literature

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Myelodysplastic syndrome and associated skin lesions: a review of the literature

Published studies are primarily clinical and epidemiological research but also basic. CiteScore measures average citations received per document published. Read more. SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact.
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Myelodysplastic syndrome and associated skin lesions: a review of the literature

Familial cases of myelodysplastic syndromes are rare, but are immensely valuable for the investigation of the molecular pathogenesis of myelodysplasia in general. The best-characterized familial myelodysplastic syndrome is that of familial platelet disorder with propensity to myeloid malignancy, caused by heterozygous germline RUNX1 mutations. Recently, there has been an increase in the number of reported cases, allowing for better understanding of the incidence, clinical features, and pathogenesis of this disorder.
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Myelodysplastic syndrome MDS is a disease entity encompassing a spectrum of clonal myeloid disorders characterized by ineffective hematopoiesis, cytopenias, qualitative disorders of blood cells and their precursors, clonal chromosomal abnormalities and a variable predilection to undergo clonal evolution to florid acute myeloid leukemia AML 1. Neutrophilic panniculitis NP is another condition that has been previously reported in five cases 1 — 5 , including four adults and a young male. The present study presents two case reports of patients with MDS associated with NP and reviews the literature on this rare condition. Written informed consent was obtained from both patients. A year-old Chinese man presented to the outpatient clinic of the Navy General Hospital Beijing, China with a 5-month history of recurrent high fever.
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