Metrics details. General practitioners encounter the vast majority of patients with Epstein-Barr virus-related disease, i. With the expanding knowledge regarding the multifaceted role of Epstein-Barr virus in both benign and malignant disease we chose to focus this review on Epstein-Barr virus-related conditions with relevance to the general practitioners. In the present review, these included three early complications; hepatitis, splenic rupture and airway compromise, as well as possible late conditions; lymphoproliferative cancers, multiple sclerosis, rheumatoid arthritis, and chronic active Epstein-Barr virus infection.
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Epstein-Barr virus EBV , also known as human herpesvirus 4, is a gamma herpes virus that occurs only in humans. Laboratory testing can help distinguish whether someone is susceptible to EBV infection or has a recent or past infection. This photomicrograph depicts leukemia cells that contain Epstein-Barr virus using an FA staining technique. EBV antibody tests are not usually needed to diagnose infectious mononucleosis.
Neutrophilic Leukocytosis in Infectious Mononucleosis: A Case Series Report
Introduction: Infectious mononucleosis IM is a common viral infection that typically causes fever, pharyngitis, and lymphadenopathy in young patients. Given that serological testing is associated with limitations regarding its accuracy, availability, and time to receive results, clinical differentiation based on symptoms, signs, and basic tests would be useful. We compared the patients' symptoms, physical findings, blood counts, and serum biomarkers to create three regression models: model 1 symptoms and signs , model 2 model 1 plus sonographic hepatosplenomegaly and blood counts , and model 3 model 2 plus hepatobiliary biomarkers.
Metrics details. A year-old Caucasian man had difficulty swallowing and shortness of breath during an episode of infectious mononucleosis. His tonsils were "kissing" and erythematous but no superimposed infection with a streptococcal organism was identified. His symptoms improved rapidly upon administration of intravenous steroids.